Letrozole: Description of the Drug
Letrozole is an oral medication primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It belongs to a class of drugs known as aromatase inhibitors, which work by decreasing estrogen levels in the body, thus hindering the growth of certain types of breast tumors that require estrogen for their development.
Mechanism of Action
The Description of the drug highlights its mechanism of action, which involves the inhibition of aromatase, an enzyme responsible for converting androgens into estrogens. By blocking this conversion process, letrozole effectively reduces circulating estrogen levels, making it particularly beneficial for patients with estrogen-sensitive breast cancer.
Indications
Letrozole is indicated for:
- Adjuvant treatment of hormone receptor-positive early breast cancer in postmenopausal https://letrozoleonline.com/products/letrozol-zentiva-filmtabletten-2-5mg-100-stuck/ women.
- First-line treatment of locally advanced or metastatic breast cancer.
- Hormone receptor-positive breast cancer recurrence prevention.
Dosing and Administration
The standard dosage of letrozole is 2.5 mg taken once daily. It’s important for patients to adhere to their prescribed regimen and consult their healthcare provider before making any changes.
Side Effects
letrozole can be effective, it may also cause side effects, including:
- Hot flashes
- Joint pain
- Fatigue
- Nausea
- Bone density loss
Considerations and Precautions
Patients considering letrozole should discuss their medical history with their healthcare provider, especially regarding:
- History of osteoporosis or fractures.
- Severe liver impairment.
- Allergic reactions to medications.
Conclusion
In summary, the description of the drug letrozole emphasizes its pivotal role in managing hormone receptor-positive breast cancer. With its specific mechanism of action and associated benefits, it remains a cornerstone treatment for many postmenopausal women facing this challenging diagnosis.